Giovedì, 05 Luglio 2018 10:31

L'Ubiquigent cerca un esperto di mass spec

Senior Scientist, Mass-Spectrometry, Ubiquigent Ltd, Dundee (June 2018)

An exciting opportunity has arisen for an experienced and motivated individual to join the biology team to help support Ubiquigent as it moves into the next phase of its development.

The overall strategy of the company is to become 'the' strategic partner for companies wishing to exploit the ubiquitin system for therapeutic benefit. The current business is based around a discovery platform focused on the ubiquitin system and accessible on either a CRO or a collaborative basis in support of clients' drug discovery programmes. In parallel the platform is being increasingly used to support the in-house development of focussed compound libraries designed to target specific ubiquitin system drug targets with the objective of delivering validated hits/leads for subsequent commercialisation/out-licensing, an approach that will become the key focus of the company as it develops.

Università degli Studi di Trento,Centre for Integrative Biology - CIBIO: PhD position: Profiling 3D Chromatin topology with high-throughput super-resolution microscopy in breast cancer

A three year PhD position is now opening at the Center for Integrative Biology CIBIO, University of Trento and the project will be carried out at the laboratory of Chromatin Biology & Epigenetics, headed by Dr. Alessio Zippo.

The project
Within the framework of the H2020-RIA "PROCHIP" consortium, the project for the PhD activity is centered on determining the contribution of chromatin organization in cancer cell heterogeneity and tumor progression. Epigenomic reprogramming plays a central role in cancer progression and metastasis formation, supporting tumour heterogeneity, which represents a challenge for precise diagnosis and targeted therapy. Defining the 3D-organization of cancer-associated chromatin domains at single cell level represents a new frontier to decipher tumor heterogeneity, acquired drug resistance and to predict the best therapeutic options.

We are looking for three highly qualified and motivated candidates s for Ph.D. positions focusing on transcription regulation during melanocyte proliferation and in mouse embryonic stem cells, and the role of autophagy in cancer, at the University of Iceland, Reykjavík.

The projects are supported by the University of Iceland Doctoral Fund and the Icelandic Research Council for three years.

The studentships are at the Biomedical Center ( and are associated with the Faculty of Medicine and the Graduate Program in Molecular Life Sciences. The graduate program is a joint program between research groups at the University of Iceland and research organizations associated with the University. The main objective of GPMLS is to create a dynamic interdisciplinary educational program and to advance research and education in the field of molecular life sciences. The program offers research and education opportunities in a stimulating environment for students working towards MSc or PhD.

| Web site |

PhD student position available in Medical Biotechnologies and Translational Medicine, section of Science and Biotechnologies of Reproduction and Development. Università degli Studi di Roma Tor Vergata

Closing date: June 11, 2018, 4pm. Further information on date of examination can be found at the following web site:

A highly motivated candidate is invited to join the group of Dr. Marco Barchi as a Ph.D. student. The group study the Mechanisms of DNA damage repair in male meiotic germ cells and germ cell tumours. In this project we will analyze the role of SPO11 protein in double strand breaks formation and chromosome segregation in male meiotic cells. This post will involve manipulating male germ cells to identify the specific function of SPO11 splice variants in meiosis. The project will make use of different knock-in and knock-out mice models developed in the lab.

Institution information: CECAD Cologne Cluster of Excellence: Cellular Stress Responses in Aging-Associated Diseases, CECAD Research Center, University of Cologne, Joseph-Stelzmann-Str. 26, D-50931 Cologne, Germany Location: Cologne is a vibrant city with a highly international academic research environment. CECAD forms a focal point of ageing research in Europe bringing together researchers and clinicians at the University of Cologne with researchers at the new Max Planck Institute for Biology of Aging in a unique research venture.

Structural Mechanisms of Ubiquitination Enzymes in Disease A PhD position is available in the lab of Sonja Lorenz at the Rudolf Virchow Center for Experimental Biomedicine, Würzburg, Germany. The Lorenz lab explores the molecular mechanisms of ubiquitin ligases and their functions in cancer (ELife 2017;6:e21036) and infection.
We are supported by the Emmy Noether Program of the German Research Foundation and the EMBO Young Investigator Program among other sources.

Three DFG-funded Ph.D. student positions are available at the Chair of Plant Systems Biology at the Life Sciences campus of the Technische Universität München in Freising-Weihenstephan.

• Cell biology of auxin transport control by regulatory protein kinases
• Control of Arabidopsis development by GATA transcription factors
• Genome-wide identification of target genes of GATA transcription factors

We are seeking three highly motivated Ph.D. students to strengthen our highly interactive and collaborative team.

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