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Programma per Venerdì 1 ottobre
Ore 11.00-13.00

Endocytosis (sala 120)
(Organizer: O. Cremona)
11.00 Role of PtdIns(4,5)P2 at the synapse
G. Di Paolo (Yale University, New Haven)
11.30 Overlap of signalling and endocytosis competent membrane microdomains
C. Tacchetti (Univ. di Genova)
12.00 Ubiquitination directs non-clathrin dependent endocytosis
S. Polo (Ist. FIRC - Univ. di Milano)
12.30 Dynamics of multivesicular endosomal membranes
J. Gruenberg (Univ. of Geneva)

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Conservation genetics (sala 300)
(Organizer: G. Bertorelle)
11.00 Introduction to the Symposium
A. Novelletto (Univ. della Calabria, Cosenza)
11.10 Studying DNA to save biodiversity: an introduction to conservation genetics
R. Frankham (Macquarie University, Australia)
12.00 New molecular data and new statistical tools: the frontiers of conservation genetics
G. Luikart (Univ. Joseph Fourier, Grenoble)
12.30 Are we protecting and restoring our genetic resources? The state of conservation genetics in Italy
G. Bertorelle (Univ. di Ferrara)

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DNA replication in microorganisms (sala 1000b)
(Organizzatori: M. Muzi-Falconi e F.M. Pisani)
11.00 Biochemical and structural characterization of an archaeal MCM helicase
Z. Kelman (Univ. of Maryland, Rockville)
11.30 DNA replication initiation factors of the archaeon Sulfolobus solfataricus
M. De Felice (CNR, Napoli)
12.00 Dynamic architecture of DNA replication forks challenged by different stresses
M. Lopes (ETH, Zurigo)
12.30 Dynamics of replication compartments in human cells during the cell cycle and in response to stress agents
A. Montecucco (CNR, Pavia)

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Neurogenesis and pattern formation in brain development (sala 1000a)
(Organizer: G. Consalez)
11.00 Molecular mechanisms shaping cerebral cortex areal profile
A. Mallamaci (Ist. Scientifico San Raffaele, Milano)
11.30 Glial cells generate neurons: molecular mechanisms of neuronal fate specification
P. Malatesta (Univ. di Parma)
12.00 The nuclear receptor COUP-TFs regulate cell migration and axonal pathways in the developing telencephalon
M. Studer (TIGEM, Napoli)
12.30 The HLH TF Ebf2 regulates cerebellar pattern formation and Purkinje cell development
G. Consalez (Ist. Scientifico San Raffaele, Milano)

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Programma per Domenica 3 ottobre
Ore 11.00-13.00


Chromatin remodeling (sala 1000a)
(Organizers: G. Piaggio and C. Gaetano)
11.00 Epigenetic regulation of gene transcription in leukemia
L. Di Croce (ICREA and CRG, Barcelona)
11.30 Histone deacetylases: a target for anti-tumor therapy
S. Minucci (Europ. Inst. Oncology, Milano)
12.00 Significant (re)location: how to use chromatin and/or abundant proteins as signals of life and death
M.E. Bianchi (Univ. Vita-Salute San Raffaele, Milano)
12.30 Bio-mechanics and chromatin remodeling
B. Illi (Ist. Dermopatico dell'Immacolata, Roma)
12.45 Chromatin and NF-Y target gene expression during muscle differentiation
A. Gurtner (Regina Elena Cancer Inst., Roma)

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Stem cell asymmetric divisions (sala 300)
(Organizer: S. Bonaccorsi)
11.00 Introduction
S. Bonaccorsi (Univ. di Roma "La Sapienza")
11.15 Asymmetric cell division in C. elegans
M. Gotta (ETH Hoenggerberg, Zurigo)
12.00 Asymmetric division of Drosophila neural progenitors
W. Chia (MRC, London)
12.30 The origin of mesoangioblasts, vessel-associated stem cells, and their possible developmental significance
G. Cossu (Univ. di Roma "La Sapienza")

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Gene expression in organelles (sala 1000b)
(Organizer: P. Vittorioso)
11.00 Role of nuclear-chloroplast interactions in the assembly of the photosynthetic apparatus and acclimation to environmental stress
R. Bassi (Univ. di Verona; Univ. Aix-Marseille II)
11.30 Regulation of mitochondrial transcription in invertebrates
P. Cantatore (Univ. di Bari)
12.00 Molecular mechanisms of gene transcription in mammalian mitochondria
C. Gustafsson (Karolinska Inst., Stockholm)
12.30 The involvement of the proteasome in mitochondrial biogenesis in S. cerevisiae
T. Rinaldi (Univ. di Roma "La Sapienza")
12.45 Inactivation of DAG1 and DAG2, two Arabidopsis zinc finger proteins, affects proteins of the chloroplast
P. Vittorioso (Univ. di Roma "La Sapienza")

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Infidelity of DNA polymerases (sala 120)
(Organizer: E. Dogliotti)
11.00 Structure-function studies of proteins that determine DNA replication fidelity
T. Kunkel (NIEHS, Research Triangle Park, NC)
11.30 Multiple functions of DNA polymerase λ: the molecular 'Swiss Army Knife'
G. Maga (CNR, Pavia)
12.00 Processing of DNA lesions by DNA polymerases from the hyper-thermophilic archaeon Sulfolobus solfataricus
F. Pisani (CNR, Napoli)
12.30 Physical and functional interactions between a DNA damage checkpoint and trans-lesion DNA synthesis
P. Plevani (Univ. di Milano)

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