PhD, postdoctoral and technician positions in cell polarity - Newcastle University, UK

  • 11 Dec 2018

Postdoctoral and research technician positions in understanding how PAR proteins cooperate to establish cell polarity

Start date: Flexible
(applicants that will need a UK Work Permit are encouraged to apply ASAP).

The laboratory of Dr Josana Rodriguez has a full-time postdoctoral and a part-time (25-50%) research technician position available. The funding is initially available for 3 years. The lab (https://www.staff.ncl.ac.uk/josana.rodriguez/) enjoys state of the art equipment and is situated in the ambitious and supportive research environment of the Institute for Cell and Molecular Biosciences (https://www.ncl.ac.uk/camb/), within the Medical School at Newcastle University (Newcastle upon Tyne, UK). We are part of a vibrant scientific community studying cell division from different angles (https://research.ncl.ac.uk/celldivisionbiology/).

We are seeking enthusiastic and highly motivated scientists keen to investigate the fundamental principles of cell polarity establishment and asymmetric cell division, both essential to tissue and organ development. We have recently uncovered novel cross-talk regulation/cooperation between key effectors of cell polarity, the PAR proteins. This project will reveal the molecular mechanisms and dynamics underlying this PAR-protein functional cooperation. We will use a multi-disciplinary approach, including proteomics, genetic screens, biochemical assays, genome editing, and cuttingedge microscopy (super-resolution). The project will use mainly the nematode C. elegans as a model, but mammalian systems are also available in the lab.

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